ETV6, BDKRB2, MME, and PRKCQ were nominally associated with angioedema (p < 0.05), but none of the candidate genes was significantly associated after correction with multiple testing (p < 2.89 × 10−5) (Fig. 3a, Table 4a, Supplementary Table S3). Here, BDKRB2 is linked to angioedema.