Figure 2 shows that basic indicators (smoking history, age, respiratory rate, number of hospitalizations and temperature), comorbidities (pulmonary heart disease,bronchiectasis,cerebrovascular disease and coronary heart disease) and inflammation (C-reactive protein, high sensitivity c-reactive protein, erythrocyte sedimentation rate, leukocyte count, absolute neutrophils and lymphocyte absolute value) are the most predictive indicators. This evidence concerns the gene CRP and cerebrovascular disorder.