DHX58 and infection: In addition, TRBP and PACT reportedly interact with LGP2 to regulate IFN production during infection with Theiler’s murine encephalomyelitis virus (TMEV) or encephalomyocarditis virus (EMCV), but not during SeV infection [28,29,30]; this finding contrasts with our result that TRBP-LGP2 interaction occurs during SeV infection [27].