In that study, Tzai et al. used an MBT-2 tumor cell line [MBT-2/TGF-beta(-)#3] treated with ASOs against TGF-β and demonstrated that the amounts of this protein were significantly decreased in both irradiated and non-irradiated MBT-2/TGF-beta(-)#3 after 48 h of in vitro culture. This evidence concerns the gene TGFB1 and neoplasm.