However, we found that tumor PD-L1 expression was not upregulated by preoperative FOLFOX chemotherapy in a population of stage IV metastatic CRC patients (post-surgical specimens: tumor PD-L1H (Figure 1E, case 1) vs. tumor PD-L1L (Figure 1E, case 2): 63% vs. 37%). The gene discussed is CD274; the disease is colorectal carcinoma.