Remarkably, within the group of HIV-positive participants, those with an enterovirus infection had significantly higher median CD4+ T cell counts compared to those that were tested enterovirus-negative (416 [IQR 168-535] vs 204 [IQR 78-460] cells/μL, p = 0.017), but did not differ in regard to antiretroviral therapy, intake of antibiotics, or time since diagnosis of HIV (Table S1 and S2). The gene discussed is CD4; the disease is enterovirus infectious disease.