In individuals with PCOS, systolic blood pressure (SBP), WHR, fasting blood glucose (FBG), 2 -hour post-glucose load blood glucose (2h-BG), fasting insulin (Fins), 2 h plasma insulin after glucose overload (2h-Ins), FFA, TC, TG, LDL-C, HOMA-IR, AUCglucose, AUCinsulin, VAI, and BAI were significantly elevated, whereas M values were markedly reduced compared to that in healthy subjects. This evidence concerns the gene INS and polycystic ovary syndrome.