Therefore, our findings were not surprising as FTO may interact with ApoA1 in regulating weight, TBW, and SLM and thus affects obesity and also corroborate studies showing SNPs from ApoA1 associated with lower levels of HDL as obesity risk factors (Rashid and Genest, 2007; Chen et al., 2009). This evidence concerns the gene FTO and obesity due to melanocortin 4 receptor deficiency.