SNCA and Parkinson disease: These mutations affect genes responsible for autosomal dominant forms of PD including genes such as α-synuclein, Park 1/4 (SNCA), Park 8 (the Leucine-Rich Repeat Kinase 2, LRRK2), and genes exhibiting an autosomal recessive mode of inheritance such as Parkin, PINK1, DJ-1, and ATP13A2.