CCDC80 and cancer: Through immunohistochemical staining of Ccdc80, we confirmed that the protein expression of Ccdc80 was significantly increased in the cancer tissues obtained from the vactosertib and Vac + nal-IRI/5-FU/LV-administered mice compared to the ones from the control and nal-IRI/5-FU/LV-administered mice (Fig. 4C).