ESR1 and neoplasm: High stathmin expression was associated with high histological grade in both cohorts (p ≤ 0.002), tumour diameter > 20 mm in cohort 1 (p = 0.018), and ER (estrogen receptor) and PR (progesterone receptor) negativity in cohort 2 (p = 0.003 and p = 0.001; Table 1).