ABCD1 and X-linked adrenoleukodystrophy: Among the VLCFA-CoAs, for example, 26:1-CoA was the most abundantly concentrated in X-ALD fibroblasts and ABCD1-KO HeLa cells and the level of 26:1-CoA was 5- to 6-fold higher than that of 26:0-CoA, while the amount of total FA 26:1 was similar to that of FA 26:0 (10, 31).