GBP5 and infection: Consistently, compared to the homozygous pigs, the pigs heterozygous for the GBP1E2, WUR and GBP5 SNP sequences exhibited significantly increased ADWG after infection with PRRSV (Figure 2C), which is also supported by previous studies investigating GBP1E2 [26] and WUR [14, 41, 42], although no significant effect was found when the pigs were co-infected with PCV2b [41].