Circulating high-density lipoproteins differed significantly by tumor CYP27A1 expression (p = 0.04; geometric means, CYP27A1-positive 64.3 mg/dl, CYP27A1-negative 68.8 mg/dl) and triglycerides differed significantly by tumor CYP7B1 expression (p = 0.02; geometric means, CYP7B1-positive 106.4 mg/dl, CYP7B1-negative 123.1 mg/dl). Here, CYP27A1 is linked to neoplasm.