A fourth ongoing phase I/II study (NCT01192555) is focusing on the administration of a biological vaccine using the same XCL1- and IL-2-producing SJNB-JF-IL2/Lptn cell line in combination with the oral drug Cytoxan, with the aim of further preventing the incomplete elimination and recurrence of high-risk neuroblastoma. The gene discussed is IL2; the disease is neuroblastoma.