SAA1 and diabetic kidney disease: SAA enrichment can impair anti-inflammatory properties of HDL as shown in patients with diabetic nephropathy [19] and may interfere with HDL’s modulation of pro-atherogenic modifications to low-density lipoprotein (LDL), endothelial cell adhesion molecules i.e., intracellular adhesion molecule/vascular cell adhesion molecule (ICAM/VCAM) expression and monocyte infiltration into the artery wall [20,21].