These findings are similar to studies that showed that an effective downregulation of the TSG101 protein by RNA interference caused reduced proliferation and colony formation, as well as an impaired migration of human prostate (PC3), breast (MDA-MB-231, MCF- 7), and renal cancer cells (A-498 and 786-O) [60,61,62]. This evidence concerns the gene TSG101 and renal carcinoma.