PRKCB and leukemia: The results indicated that 2b inhibited at values ranging from 70% to 98% the biochemical activity of IKK-α (70%), IRK (86%), PKC-β (79%), RAF-1 (79%), Src (94%), TRKA (98%) kinases, all of them found involved in leukemia initiation and development [37,38,39,40,41,42].