The research reports from Chen et al. [83] showed that the intratumoral injection of measles virus vaccine strain Edmonston (MV-EDM) could induce the expression of specific ligand MICA and MICB on the surface of hepatoma cells, and thereby could significantly enhance the cytotoxicity of CD8+NKG2D+ T cells to hepatocellular carcinoma. This evidence concerns the gene KLRK1 and hepatocellular carcinoma.