STS has not been tested in a PE setting before, our findings are in line with a previous study that demonstrated STS’s antihypertensive effect in an angiotensin-II male rat model of cardiac disease, and further substantiate a large body of literature that implicates a deficit in H2S in the pathophysiology of hypertension [9,16,25,26]. The gene discussed is AGT; the disease is hypertensive disorder.