Moreover, it had been known that vascular calcification is a process of gradual osteogenesis initiated by inflammatory factors in vessels and it was found that higher serum CRP was associated with the presence of aortic calcification in CKD patients [17] as well as in HD and PD patients in addition to old age, hypoalbuminemia, and DM [16,25]. The gene discussed is CRP; the disease is Hypoalbuminemia.