Protein expression of EAAT2 in glutamatergic pathway was found upregulated in CRS group (P=0.04; Figure 4B), whereas no changes were found in protein expression levels of TH, AADC, MAOA, VMAT2, GAD1, GLUL and SNAT1 (Figure 4). The gene discussed is TH; the disease is congenital rubella syndrome.