Our patients had not yet presented tumor manifestations, and this may be due to the detected hypoexpression of several tumorigenesis‐related genes such as GLI1, KIT, WNT7A, AXIN2, FGFR1, FZD3, FZD6, ITGA6, PDGFB, PLEKHG5, and PRKC. The gene discussed is FZD3; the disease is neoplasm.