qPCR results also revealed an increase of TNF‐α, IL‐6 and CCR7, but an decrease of IL‐10 in ApoE‐/‐ mice, indicating that hyperlipidemia affected the inhibitory effects of lisinopril on the maturation of spleen‐derived DCs and inflammatory response after MI (Figure 3A‐D). Here, APOE is linked to hyperlipidemia.