EGFR and intraepithelial neoplasia: For instance, for the parameter representing the EGFR → JAK regulation, the null hypothesis of equal distribution is not rejected when comparing the two primary tumors (lower two boxes in gold) between themself and with respect to intraepithelial neoplasia (top‐left box, half gold next to the corresponding interaction in Fig 3A); however, it is rejected when comparing each of them with liver metastasis (top‐right box, in cyan).