Kinase activity blocks the transmission of the VEGF/VEGFR‐2 signaling pathway and inhibits tumor angiogenesis, thereby inhibiting tumor growth.25, 26 At present, apatinib is mainly used in the treatment of advanced gastric cancer as a third‐line or higher treatment.27 Furthermore, a series of clinical trials of apatinib in the treatment of advanced lung cancer initially confirmed that apatinib can effectively slow the growth of lung cancer. The gene discussed is VEGFA; the disease is lung carcinoma.