ADNP and ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder: Recently, heterozygous dominant, disease inflicting de novo mutations in ADNP have been identified in cohorts of intellectually disabled (ID) children suffering from syndromic ASD and calculated to affect 0.17% of the autistic children—defining the ADNP syndrome (Gozes et al. 2015a, 2017a, b; Helsmoortel et al. 2014; Levine et al. 2019; Mollinedo et al. 2019; O'Roak et al. 2012) (OMIM 611386 and Orphanet—https://www.orpha.net/consor/cgi- bin/OC_Exp.php?Lng = EN&Expert = 404448).