Finally, Huang et al. showed that Lactobacillus paracasei (LP), Lactobacillus fermentum (LF), or their combination, given to asthmatic children aged 6 to18 years as capsules for 3 months, lowered the asthmatic severity, improved asthma control, increased the peak expiratory flow rate, and decreased IgE levels [151]. This evidence concerns the gene IGHE and asthma.