Jemli et al. (2017) researched the association between the functional polymorphism of IFNGR2 with SCZ and found the IFNGR2 Q64R polymorphism was associated with SCZ in males. The study conducted by Yang et al. (2016) showed that the genotypes and allele distributions of rs3087494 in PLA2G12A were significantly associated with SCZ in males, but not in females. Another study focused on sex-specific molecular phenotypes found that eight genes showed a differential expression in female and male schizophrenia patients (Ramsey et al., 2013). The gene discussed is IFNGR2; the disease is schizophrenia.