SMYD3 and hepatocellular carcinoma: A corresponding result was observed when comparing the median of SMYD3 levels in non-HCC and in HCC patients (251.1 pg/mL and 311.8 pg/mL, respectively, P = 0.04; Fig. 1D), whereas the median of SMYD3 levels did not differ between non-LC and LC individuals (Fig. 1C).