We identified 3 distinct CRC subgroups, described as cluster 1 (N = 1, T20), cluster 2 (N = 2, T45 & T67) and cluster 3 (N = 3, T31, T65 & T35), having mutation status of positive BRAF and negative KRAS in cluster 1, negative BRAF and negative KRAS in cluster 2 and negative BRAF and positive KRAS in cluster 3. Here, BRAF is linked to colorectal carcinoma.