In cancer, TF is highly expressed on the cancer cells in many types of solid cancers14,23,30–32, acute myeloid and lymphoblastic leukemia (AML and ALL) and sarcoma23,32 as well as in Hodgkin’s lymphoma33 and multiple myeloma (MM, TF detected in 10 out of 18 patients with MM and 3 MM lines)34. Here, TF is linked to acute myeloid leukemia.