Although T cell infiltration in ICB NR tumors was significantly lower compared to ICB R tumors (Fig. 3a, Supplementary Fig. 4a), no alterations in relative frequencies of CD8+ and CD4+ tumor-infiltrating lymphocytes (TILs) of ICB R compared to NR mice were observed (Supplementary Fig. 4a). The gene discussed is CD8A; the disease is neoplasm.