CSF1R blockade by monoclonal antibodies increased therapy response from 33.33% (ICB) to 54.53% (ICB + CSF1R blockade) with only 2 out of 11 mice showing tumor progression of >40% between MRI2 and MRI3 (compared to 6 out of 12 in the ICB cohort; Fig. 4b, Supplementary Fig. 7a, b). This evidence concerns the gene CSF1R and neoplasm.