FIR family (FIR, FIRΔexon2, and PUF60), Snai1, and BRG1 increased, but FBW7 and E-cadherin decreased in human gastric cancers, as shown by immunohistochemical staining (Fig. 5a, Supplementary Figs. S4 and S5); however, the expression of BRG1 was reduced in some cases (Fig. 4a and Supplementary Fig. S4). The gene discussed is FBXW7; the disease is gastric cancer.