FGF8 and cancer: Expectedly, FIR or FIRΔexon2 affected to the alternative splicing of FGF8 mRNA expression revealed by PCR analysis in cancer cell lines, MCF-7, HeLa, and Jurkat cells (Lanes 1 and 7; 100 bp marker, lane 2: HeLa cells, lane 3; MCF-7 cells, lane 4; Jurkat cells, lane 5; negative control, lane 6; FGF8 positive control; Fig. 2a).