Finally, the relationship between SLX4IP and TERT expression in dictating breast cancer cell sensitivity also extends to the members of the murine 4T1 breast cancer progression series, which comprises (i) 67NR cells, which are weakly tumorigenic and nonmetastatic, (ii) 4T07 cells, which are systemically invasive, and (iii) 4T1 cells, which are highly metastatic (Aslakson & Miller, 1992). This evidence concerns the gene TERT and breast carcinoma.