TBR1 and renal cell adenocarcinoma: Statistical evaluation of the candidate TBR1 locus using the evaluation tissue cohort of primary tumors did not reveal any significant relationship in bivariate logistic regression analyses for the group of all RCC or ccRCC when including age as covariate for the clinic-pathological parameters of clinical state of distant (P = 0.27 and P = 0.70 for all RCC and ccRCC groups) and lymph node (P = 0.44 and P = 0.53) metastasis, high (> = G2–3) vs. low (< = G2) histological grade (P = 0.12 and P = 0.34) and high (> = T3) vs. low (< = T2) clinical stage (P = 0.21 and P = 0.12).