Further analysis revealed that higher expression levels of six subunits, i.e., CHD4, HDAC1, KDM1A, MTA3, RBBP4, RBBP7, were associated with more advanced stage, higher grade, and poorer prognosis, proving the importance of the NuRD complex with this specific composition in HCC. Here, CHD4 is linked to hepatocellular carcinoma.