Given that VEGFA is the most important regulator of tumor angiogenesis, Bevacizumab (Avastin), a humanized monoclonal anti-VEGFA antibody, is a typical example of anti-tumor angiogenesis and it is now used as anti-angiogenic drug in several forms of cancers, including breast, colorectal, and lung cancers [123]. Here, VEGFA is linked to lung carcinoma.