The results revealed that the expression of 29 glycolysis and gluconeogenesis related genes including SLC2A1, HK2, GPI, PFKP, ALDOA, TPI1, GAPDH, PGK1, PGAM1, ENO1, PKM, LDHA, etc. were significantly higher in tumor tissues compared with normal mammary tissues. The gene discussed is PGAM1; the disease is neoplasm.