Notably, deficiency of the IL17RA, IL17RC, IL17F, or TRAF3IP2 genes is implicated in chronic mucocutaneous candidiasis disease (CMCD), which is characterized by recurrent or persistent infection affecting the nails, skin, and oral and genital mucosae caused by the Candida species, often C. albicans [96,111,112,113]. This evidence concerns the gene IL17RC and cutaneous mastocytosis.