Comparing the AKT1 E17K tumour tissues to the NF2-negative grade I meningiomas showed that AKT1 E17K mutants contained significantly fewer CD68 macrophages (7.4 vs. 10.7%; p = 0.036; Figure 3) and CD163-positive cells (8.4 vs. 12.9%; p = 0.049; Figure 4) compared to NF2 meningiomas, supporting the flow cytometry data suggesting that genotype may influence immune cell filtration over the course of tumour development. Here, AKT1 is linked to neoplasm.