A total of 171 meningiomas were screened using a KASPTM genotyping panel containing the following somatic coding mutations: AKT1 E17K, KLF4 K409Q, PIK3CA E545K, PIK3CA H1047R, POLR2A Q403K, POLR2A L438-H439del, SMARCB1 R374Q, SMARCB1 R377H, SMO L412F and SMO W535L (Table 1). The gene discussed is AKT1; the disease is meningioma.