Furthermore, studies performed on esophageal, oral, skin, regulatory T-cells, lung, breast, and prostate cancer cells reported alterations induced by bioactive compounds from green tea, including EGCG, on DNMT activity in studies performed on esophageal, oral, skin, regulatory T-cells, lung, breast, and prostate cancer cells [270]. The gene discussed is DNMT1; the disease is Familial prostate cancer.