EMD and osteosarcoma: Overall, the intensity profiles of the lamins and emerin were brilliant (Figure 4B,B’), and the frequency of their mean value distribution were significantly different, being lamin A/C and emerin less expressed in MG63 than OBs, while lamin B1 mean fluorescence intensity was higher in the osteosarcoma cell line, in comparison to normal OBs (Figure 4C).