Niclosamide has been shown to inhibit a number of signaling pathways including nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) [15], mammalian target of rapamycin complex 1 (mTORC1) [16], signal transducer and activator of transcription 3 (STAT3) [17], and Wnt/B-catenin [18] in several cancer cells. The gene discussed is STAT3; the disease is cancer.