FBXW7 and posterior cortical atrophy: The reconstitution of miR-1272 expression in PCa cells, inherently expressing negligible levels of the miRNA, resulted in a marked abrogation of its predicted target HIP1. Notably, the results of 6 Ago-CLIP sequencing experiments collected in Mtibase (Table 1) confirmed that miR-1272 binding site within HIP1 3′UTR is not merely predicted in silico but is also physically bound by Ago proteins within RNA-induced silencing complex.