In addition, we showed that, when restored in a couple of metastatic PCa cell lines, miR-1272 is able to hinder EMT, drastically reduce migration and invasion, limit cell growth and act as radiosensitizer by reducing the levels of Huntingtin Interacting Protein 1 (HIP1), whose overexpression has been associated with PCa and correlated with the severity of the disease. The gene discussed is HIP1; the disease is posterior cortical atrophy.