TGFB1 and cirrhosis of liver: Moreover, alterations of serum miR-571 levels in patients with chronic liver disease and its up-regulation in human hepatocytes and hepatic stellate cells in response to the pro-fibrogenic cytokine TGF-β reflected their putative roles as a mediator of fibrogenic and inflammatory processes in distinct cellular compartments involved in the pathogenesis of liver cirrhosis [85].