Subsequently, a recent multicenter, adequately powered RCT including 2203 infants <34 weeks (the Enteral Lactoferrin supplementation For very preterm INfants ELFIN trial) showed no difference in any of the measured morbidities, including necrotizing enterocolitis (NEC), late onset sepsis and BPD [17], dismissing lactoferrin for BPD prevention. This evidence concerns the gene LTF and necrotizing enterocolitis.