Other non-IgE-mediated GI diseases, such as eosinophilic esophagitis, eosinophilic gastritis and eosinophilic gastroenteritis, may induce chronic or intermittent emesis, gastroesophageal reflux (GER) and poor appetite, often leading to FTT in children [11]. This evidence concerns the gene IGHE and eosinophilic esophagitis.