These include SOX9 [36, 37], which plays an important role in tracheal and lung epithelium development, GATA6 [38, 39], a regulator for AT1/AT2 cell type, SREBF1 which regulates the biological process of perinatal lung maturation [40], STAT6 which can serve as a therapeutic target for preventing pulmonary hypoplasia [41], YY1 [42], which is required in lung morphogenesis and CEBPB plays pivotal role in determining airway epithelial differentiation [43]. This evidence concerns the gene SOX9 and Pulmonary hypoplasia.