CXCL5 and CXCL1 can promote intratumoral neutrophil infiltration, and their overexpression has been correlated with poor prognosis in HCC.21, 22, 23 CDK4 is a promising anticancer target in several cancers, including hepatocellular carcinoma. The gene discussed is CXCL5; the disease is hepatocellular carcinoma.